Toxins love to get you while you're young. Lead, mercury, secondhand smoke and sundry other environmental nasties do a lot more damage when tissue is immature, vulnerable and growing than when it's mature and comparatively fixed.

• There are a lot of downsides to being male. We age faster and die younger. But give us this: we're lifetime baby-making machines. Women's reproductive abilities start to wane when they're as young as 35. Men? We're good to go pretty much till we're dead.
• Older fatherhood isn't all bad: testosterone rates drop about 1% per year as men age, making them less reactive and more patient, and a professionally established middle-aged man is likely to have more time and money to devote to his kids than a twenty-something who's just getting started.
• Credit or debit cards, for starters, are nothing short of shoppers' Novocain. Even in the age of digital purchases and virtual money, we still attach a special value to dirty paper with pictures of presidents on it. Handing some of that to a cashier simply hurts more than handing over a little sliver of plastic.
• When it comes to raising civilized kids there are no hard rules, but there are two things on which most parents agree: Boys are generally wilder than girls, and adolescents are wilder than kids of any other age. If you've got an adolescent boy, you're in the sweet spot for trouble.
• At the root of the shy temperament is a deep fear of social judgment, one so severe it can sometimes be crippling. Introverted people don't worry unduly about whether they'll be found wanting, they just find too much socializing exhausting and would prefer either to be alone or in the company of a select few people.
• Becoming food savvy is one thing, but it's amazing how fast savvy turns to snooty, and snooty leaves you preparing three-hour meals that break your budget and that the kids won't even eat.
• It's far too much to say that effective hoping is the only - or even the biggest - part of what it takes to succeed. If 14% of business productivity can be attributed to hope, that means 86% is dependent on raw talent, fickle business cycles, the quality of the product you're selling, and often pure, dumb luck.
• Spending $1 for a brand new house would feel very, very good. Spending $1,000 for a ham sandwich would feel very, very bad. Spending $19,000 for a small family car would feel, well, more or less right. But as with physical pain, fiscal pain can depend on the individual, and everyone has a different threshold.
• Paul McCartney had a baby when he was 61 Rod Stewart was 66 Rupert Murdoch was a stunning 72. Not only does that mean they'll have less stamina than the average dad, that means they'll, well, check out a lot sooner too.
• The golden child may be the oldest one, unless it's the youngest. It may be the toughest one, unless it's the most sensitive. It's not even necessary that Mom and Dad have the same favorite - and typically they don't.